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Delicious cattle drive casserole made with ground beef and fresh ingredients

Cattle Drive Casserole

A hearty casserole featuring seasoned ground beef, creamy layers of sour cream and cheese, all nestled in a fluffy biscuit base, perfect for family gatherings or busy weeknights.
Prep Time 20 minutes
Cook Time 40 minutes
Total Time 1 hour
Course Dinner, Main Course
Cuisine Tex-Mex
Servings 8 servings
Calories 400 kcal

Ingredients
  

Meat and Vegetables

  • 1.5 pounds lean ground beef Use lean beef to avoid greasiness.
  • 1 ounce taco seasoning mix Adds flavor.
  • 1 red bell pepper seeded and chopped Fresh vegetables add color and nutrition.
  • 1 yellow onion chopped Enhances flavor.

Biscuit Base

  • 2.5 cups biscuit mix Can use Bisquick or make homemade mix.
  • 1 cup water For mixing with biscuit mix.

Creamy Layers

  • ½ cup sour cream Can substitute with Greek yogurt for lower calories.
  • ½ cup mayonnaise Adds creaminess.
  • 4 ounces diced green chiles Drained.
  • 1.5 cups shredded Cheddar cheese Use a Fiesta blend for flavor.
  • 1 teaspoon garlic powder Adds flavor.
  • ½ cup mild salsa For added flavor and moisture.

Miscellaneous

  • cooking spray like Pam For greasing the casserole dish.

Instructions
 

Preparation

  • Preheat your oven to 350°F.
  • In a large skillet over medium-high heat, cook the ground beef until browned, breaking it apart with a spoon. Drain any excess fat.
  • In a mixing bowl, combine biscuit mix and water for the biscuit dough; thoroughly mix and press into a greased casserole dish.
  • Bake the biscuit layer in the preheated oven for 5-8 minutes until lightly golden. Set aside but keep the oven on.
  • Add the chopped onion and red bell pepper to the cooked beef and stir; cook for about 4 minutes. Add taco seasoning and mix well.

Assembly

  • Spread the cooked beef mixture evenly over the baked biscuit base.
  • In a medium bowl, mix sour cream, mayonnaise, green chiles, ¾ cup shredded cheese, and garlic powder until smooth; spread over the beef layer.
  • Spoon salsa on top of the sour cream layer and sprinkle remaining shredded cheese over everything.

Baking

  • Return the casserole to the oven, uncovered, and bake for about 30 minutes until hot and bubbly.

Notes

Garnish with fresh cilantro or green onions. Pairs well with a green salad or tortilla chips. Store leftovers in the fridge for up to 3-4 days or freeze for longer storage.
Keyword Cattle Drive Casserole, comfort food, Family Meal, Hearty Casserole, One-Dish Dinner